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Immunol Allergy Clin North Am. 2015 Nov;35(4):599-623. doi: 10.1016/j.iac.2015.07.001. Epub 2015 Aug 25.

Overview of Immunodeficiency Disorders.

Author information

1
Children's Mercy Hospital, University of Missouri-Kansas City, 2401 Gillham Road, Kansas City, MO 64108, USA. Electronic address: nraje@cmh.edu.
2
Children's Mercy Hospital, University of Missouri-Kansas City, 2401 Gillham Road, Kansas City, MO 64108, USA.

Abstract

The spectrum of primary immunodeficiency disorders (PIDs) is expanding. It includes typical disorders that primarily present with defective immunity as well as disorders that predominantly involve other systems and show few features of impaired immunity. The rapidly growing list of new immunodeficiency disorders and treatment modalities makes it imperative for providers to stay abreast of the latest and best management strategies. This article presents a brief overview of recent clinical advances in PIDs.

KEYWORDS:

Antibody deficiency; Autoimmunity; Immune defect; Immune dysregulation; Immunodeficiency; Innate immune defect; Lymphoproliferation

PMID:
26454309
PMCID:
PMC4600970
DOI:
10.1016/j.iac.2015.07.001
[Indexed for MEDLINE]
Free PMC Article

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