Send to

Choose Destination
Neuron. 2015 Oct 7;88(1):20-32. doi: 10.1016/j.neuron.2015.09.004.

The Consolidation and Transformation of Memory.

Author information

Department of Neurobiology, Weizmann Institute of Science, Rehovot 76100, Israel; Center for Neural Science, New York University, New York, NY 10003, USA. Electronic address:
Sagol Department of Neurobiology and Department of Human Biology, University of Haifa, Mount Carmel 31905, Israel.
Center of Integrative Neuroscience and Institute of Medical Psychology and Behavioral Neurobiology, University of Tuebingen, 72076 Tuebingen, Germany. Electronic address:


Memory consolidation refers to the transformation over time of experience-dependent internal representations and their neurobiological underpinnings. The process is assumed to be embodied in synaptic and cellular modifications at brain circuits in which the memory is initially encoded and to proceed by recurrent reactivations, both during wakefulness and during sleep, culminating in the distribution of information to additional locales and integration of new information into existing knowledge. We present snapshots of our current knowledge and gaps in knowledge concerning the progress of consolidation over time and the cognitive architecture that supports it and shapes our long-term memories.

[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center