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Nat Rev Gastroenterol Hepatol. 2015 Nov;12(11):611-3. doi: 10.1038/nrgastro.2015.170. Epub 2015 Oct 6.

Viral hepatitis: A new HCV cell culture model for the next clinical challenges.

Author information

1
Inserm, U1110, Institut de Recherche sur les Maladies Virales et Hépatiques, Université de Strasbourg, 67000 Strasbourg, France.

Abstract

Despite advances in hepatitis C treatment, substantial clinical hurdles remain to achieve universal cure and global control of infection. Saeed et al. identified SEC14L2 as a host factor permitting replication of clinical HCV isolates in cell culture, providing a novel system to model infection of patient-derived viruses.

PMID:
26441247
DOI:
10.1038/nrgastro.2015.170
[Indexed for MEDLINE]

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