Interleukin-18 disruption suppresses hypoxia-induced pulmonary artery hypertension in mice

Int J Cardiol. 2016 Jan 1:202:522-4. doi: 10.1016/j.ijcard.2015.09.118. Epub 2015 Oct 3.

Affiliations

¹ Cardiovascular Division, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.
² Cardiovascular Division, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan. Electronic address: hirotani@hyo-med.ac.jp.
³ Laboratory of Tumor Immunology and Cell Therapy, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.

PMID: 26440469
DOI: 10.1016/j.ijcard.2015.09.118

No abstract available

Publication types

Letter

MeSH terms

Animals
Hypertension, Pulmonary / etiology
Hypertension, Pulmonary / metabolism*
Hypertension, Pulmonary / prevention & control*
Hypoxia / complications
Hypoxia / metabolism*
Hypoxia / prevention & control*
Interleukin-18 / deficiency*
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
NF-kappa B / metabolism*

Substances

Interleukin-18
NF-kappa B