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J Neuroimmunol. 2015 Oct 15;287:27-8. doi: 10.1016/j.jneuroim.2015.08.001. Epub 2015 Aug 6.

Hypertrophic pachymeningitis accompanying neuromyelitis optica spectrum disorder: A case report.

Author information

1
Department of Neurology, Aomori Prefectural Central Hospital, Aomori, Japan. Electronic address: t-kon@umin.ac.jp.
2
Department of Neurology, Aomori Prefectural Central Hospital, Aomori, Japan.
3
Department of Neurology, Tohoku University School of Medicine, Sendai, Japan; Department of Neurology, Yonezawa National Hospital, Yonezawa, Japan.

Abstract

We report a case of idiopathic cerebral hypertrophic pachymeningitis accompanying neuromyelitis optica spectrum disorder. No other identifiable cause of pachymeningitis was detected. Corticosteroid therapy was effective for both diseases. Hypertrophic pachymeningitis is closely related to autoimmune inflammatory disease of the central nervous system. This case supports the hypothesis that hypertrophic pachymeningitis can be a rare comorbidity of neuromyelitis optica spectrum disorder.

KEYWORDS:

Aquaporin-4 antibody; Autoimmune disease; Hypertrophic pachymeningitis; Neuromyelitis optica; Neuromyelitis optica spectrum disorders

PMID:
26439957
DOI:
10.1016/j.jneuroim.2015.08.001
[Indexed for MEDLINE]

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