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Exp Dermatol. 2016 Feb;25(2):157-9. doi: 10.1111/exd.12863. Epub 2015 Nov 23.

Secukinumab distributes into dermal interstitial fluid of psoriasis patients as demonstrated by open flow microperfusion.

Author information

1
Health - Institute for Biomedicine and Health Sciences, Joanneum Research Forschungsgesellschaft m.b.H., Graz, Austria.
2
Novartis Institutes for BioMedical Research, Basel, Switzerland.
3
Department of General Dermatology, Medical University of Graz, Graz, Austria.
4
Division of Endocrinology and Metabolism, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
5
Beijing Novartis Pharma Co. Ltd., Shanghai, China.

KEYWORDS:

dermal open flow microperfusion; monoclonal antibody; pharmacokinetics; psoriasis; secukinumab

PMID:
26439798
DOI:
10.1111/exd.12863
[Indexed for MEDLINE]

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