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Worm. 2015 Mar 6;4(2):e1021109. doi: 10.1080/21624054.2015.1021109. eCollection 2015 Apr-Jun.

Workshop report: Caenorhabditis nematodes as model organisms to study trait variation and its evolution.

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Institut de Biologie Valrose ; CNRS UMR7277 ; Parc Valrose; Nice, France ; INSERM U1091 ; Nice, France ; Université Nice Sophia Antipolis; UFR Sciences ; Nice, France.
Institut de Biologie de l ´École Normale Supérieure (IBENS) ; CNRS UMR8197 ; Paris, France.


A fundamental problem in biology is to understand how genome expression translates into variation in molecular, cellular, developmental, physiological, behavioral, or life-history traits. During the summer of 2014, worm biologists with a keen interest in evolutionary biology and natural ecology met in Les Treilles (France) to define the problems of trait variation better and to discuss empirical approaches using Caenorhabditis species to address these problems. Compared with other model organisms, Caenorhabditis has several advantages, such as well-defined traits that can be subjected to highly controlled environmental and genetic manipulation and the possibility for long-term experimental evolution that can be coupled with genome-wide mapping of trait variation. The Les Treilles workshop brought together researchers studying the evolution of phenotypic plasticity, gene-networks, genome structure and population genetics, sex-determination and development in the laboratory, behavior and the life-history of natural Caenorhabditis populations. Here, we outline the key aims of this workshop and summarize the contributions of each participant.


fluctuating environments; genotype-by-environment interactions; genotype-phenotype map; phenotypic plasticity; variation

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