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Tumori. 2016 Nov 11;102(Suppl. 2):116-118. doi: 10.5301/tj.5000437. Epub 2015 Sep 30.

Mass-forming extramedullary hematopoiesis in multiple myeloma: 18F-FDG PET/CT is useful in excluding extramedullary myeloma involvement.

Author information

1
Department of Nuclear Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan - Korea.
2
Department of Hematology and Cellular Therapy, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan - Korea.
3
Department of Pathology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan - Korea.
4
Department of Laboratory Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan - Korea.

Abstract

AIMS AND BACKGROUND:

Extramedullary hematopoiesis (EMH), a benign condition, is usually observed in patients with hematologic disorders. We report the first case of mass-forming EMH detected on a 18F-fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) scan in a patient with multiple myeloma (MM).

METHODS:

A 58-year-old woman underwent workup for bicytopenia, and was diagnosed with MM based on the results of bone marrow aspiration and serum protein electrophoresis. An 18F-FDG PET/CT scan revealed a paravertebral mass with mild FDG avidity, suggesting a tumorous condition.

RESULTS:

Biopsy was performed to exclude malignancy and the mass was eventually confirmed as EMH.

CONCLUSIONS:

Differential diagnosis of a mildly FDG-avid paravertebral mass in MM should include EMH.

PMID:
26429647
DOI:
10.5301/tj.5000437
[Indexed for MEDLINE]

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