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J Autism Dev Disord. 2016 Feb;46(2):673-84. doi: 10.1007/s10803-015-2582-7.

Nutritional Impact of a Gluten-Free Casein-Free Diet in Children with Autism Spectrum Disorder.

Author information

1
Unit of Public Health and Environmental Care, Department of Preventive Medicine, University of Valencia, Valencia, Spain.
2
Institute of Health Carlos III, CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
3
Center for Public Health Research (CSISP-FISABIO), Valencia, Spain.
4
Department of Nutrition and Food Sciences and Physiology, University of Navarra, Navarra, Spain.
5
Biomedical Research Centre Network on Obesity and Nutrition (CIBERobn), Physiopathology of Obesity and Nutrition, Institute of Health Carlos III, Madrid, Spain.
6
Clinical Nutrition and Dietetics Unit, Navarra Hospital Complex, Navarra, Spain.
7
Unit of Public Health and Environmental Care, Department of Preventive Medicine, University of Valencia, Valencia, Spain. maria.m.morales@uv.es.
8
Institute of Health Carlos III, CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain. maria.m.morales@uv.es.
9
Center for Public Health Research (CSISP-FISABIO), Valencia, Spain. maria.m.morales@uv.es.

Abstract

We compared anthropometric values, nutrient intake, the Healthy Eating Index and food variety in children with autism spectrum disorder (ASD), 20 on a gluten-free casein-free (GFCF) diet and 85 on a regular diet in Valencia (Spain) using 3-days food diaries. Those on the GFCF diet had a lower weight, body mass index, and total energy, pantothenic acid, calcium, phosphorus and sodium intake, but a higher intake of fiber, legumes, and vegetables. Further, the GFCF diet group had a better quality of fat intake, but needed supplementation with vitamin D. Randomized controlled trials are required to explore long-term effects of this diet on anthropometric and nutritional status (the focus of our study), but also behavioral symptoms, in children with ASD.

KEYWORDS:

ASD (autism spectrum disorder); Casein-free diet; Gluten-free; Growth; Nutrition

PMID:
26428353
DOI:
10.1007/s10803-015-2582-7
[Indexed for MEDLINE]

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