Send to

Choose Destination
Ann Indian Acad Neurol. 2015 Jul-Sep;18(3):335-7. doi: 10.4103/0972-2327.157180.

"Nine" syndrome: A new neuro-ophthalmologic syndrome: Report of two cases.

Author information

Department of Neurology, Mathikere Sampangappa Ramaiah Medical College and Hospital, Bangalore, Karnataka, India.


"Eight-and-a-half" syndrome is a rare condition involving the ipsilateral abducens nucleus or paramedian pontine reticular formation (PPRF), the ipsilateral medial longitudinal fasciculus (MLF), and the adjacent facial colliculus/facial nerve fascicle. The condition is often caused by a lesion (vascular or demyelinating) in the dorsal tegmentum of the caudal pons. There are new variants of this syndrome caused by extension of lesion to involve new adjacent structures in pontine tegmentum. We report two patients with different etiology presenting with clinical features suggestive of eight-and-a-half syndrome associated with hemiataxia representing "nine" syndrome (8½ + ½ = 9) adding new dimension to "eight-and-a-half" syndrome.


Demyelination; eight-and-a-half syndrome; hemorrhage; medial longitudinal fasciculus; paramedian pontine reticular formation; pons; tegmentum

Supplemental Content

Full text links

Icon for Medknow Publications and Media Pvt Ltd Icon for PubMed Central
Loading ...
Support Center