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J Clin Microbiol. 2015 Dec;53(12):3912-5. doi: 10.1128/JCM.02578-15. Epub 2015 Sep 30.

Characterization of Five Zoonotic Streptococcus suis Strains from Germany, Including One Isolate from a Recent Fatal Case of Streptococcal Toxic Shock-Like Syndrome in a Hunter.

Author information

1
Hessian State Laboratory, Department of Veterinary Medicine, Giessen, Germany.
2
Institute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, Philipps University Marburg, Marburg, Germany.
3
Institute of Medical Microbiology, Justus Liebig University Giessen, Giessen, Germany.
4
Medical Clinic II, Justus Liebig University Giessen, Gissen, Germany.
5
Central Facility for Microscopy, Helmholtz Centre for Infection Research, Braunschweig, Germany.
6
Institute for Microbiology, University of Veterinary Medicine Hannover, Hannover, Germany.
7
Institute for Microbiology, University of Veterinary Medicine Hannover, Hannover, Germany Institute for Bacteriology and Mycology, Centre of Infectious Diseases, College of Veterinary Medicine, University Leipzig, Leipzig, Germany christoph.baums@vetmed.uni-leipzig.de.

Abstract

A Streptococcus suis isolate from a German hunter with streptococcal toxic shock-like syndrome (STSLS) and four additional zoonotic isolates were genotyped as mrp(+) epf* (variant 1890) sly(+) cps2(+). All five zoonotic German strains were characterized by high multiplication in human blood samples ex vivo, but induction of only low levels of proinflammatory cytokines compared to a Chinese STSLS strain.

PMID:
26424844
PMCID:
PMC4652130
DOI:
10.1128/JCM.02578-15
[Indexed for MEDLINE]
Free PMC Article

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