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Adv Mater. 2015 Nov;27(42):6644-50. doi: 10.1002/adma.201503095. Epub 2015 Sep 28.

3D Printed Microtransporters: Compound Micromachines for Spatiotemporally Controlled Delivery of Therapeutic Agents.

Author information

1
Institute of Robotics and Intelligent Systems, ETH Zurich, Zurich, CH 8092, Switzerland.
2
School of Electronics and Information Engineering, Liaoning University of Science and Technology, Anshan, 114051, China.
3
Wyss Institute for Biologically Inspired Engineering, School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, 02318, USA.
4
Department of Electrical, Computer, and Biomedical Engineering, Department of Chemical Engineering, University of Rhode Island, Kingston, RI, 02881, USA.

Abstract

Functional compound micromachines are fabricated by a design methodology using 3D direct laser writing and selective physical vapor deposition of magnetic materials. Microtransporters with a wirelessly controlled Archimedes screw pumping mechanism are engineered. Spatiotemporally controlled collection, transport, and delivery of micro particles, as well as magnetic nanohelices inside microfluidic channels are demonstrated.

KEYWORDS:

3D printing; magnetism; micromachines; microrobotics; targeted cell delivery; targeted drug delivery

PMID:
26415002
PMCID:
PMC4669391
DOI:
10.1002/adma.201503095
[Indexed for MEDLINE]
Free PMC Article

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