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Zhongguo Dang Dai Er Ke Za Zhi. 2015 Sep;17(9):980-3.

[Relationship between serum zinc levels and attention deficit hyperactivity disorder in children].

[Article in Chinese]

Author information

1
Department of Epidemiology, Public Health School of Xuzhou Medical College, Xuzhou, Jiangsu 221000, China. sunguixiang1974@163.com.

Abstract

OBJECTIVE:

To study the possible relationship between serum zinc levels and attention deficit hyperactivity disorder (ADHD) in Chinese children.

METHODS:

Following a systematic search for case-control studies on the serum zinc levels in Chinese children with ADHD published between 2000 and 2015, a Meta analysis was conducted using Stata 12.0 software.

RESULTS:

A total of 17 studies, including 2 177 children with ADHD and 2 900 normal children, were enrolled. The Meta analysis showed that serum zinc levels in children with ADHD were lower than normal children (SMD= -1.33; 95%CI: -2.22, -0.44; P=0.003). The sensitivity analysis indicated that the results were reliable. Eggerγs test did not find the existence of publication bias.

CONCLUSIONS:

Serum zinc levels may be associated with susceptibility to ADHD in children.

PMID:
26412183
[Indexed for MEDLINE]
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