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Pathog Dis. 2015 Nov;73(8):ftv076. doi: 10.1093/femspd/ftv076. Epub 2015 Sep 26.

Diarrhea, bacteremia and multiorgan dysfunction due to an extraintestinal pathogenic Escherichia coli strain with enteropathogenic E. coli genes.

Author information

1
Division of Infectious Diseases, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
2
The Institute for Genome Sciences and Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
3
Pathology and Laboratory Service, University of Maryland School of Medicine, VA Maryland Health Care System, Baltimore, MD 21201, USA.
4
Division of Infectious Diseases, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA mdonnenb@umaryland.edu.

Abstract

A 55-year-old man with well-controlled HIV had severe diarrhea for 3 weeks and developed multiorgan dysfunction and bacteremia due to Escherichia coli. The genome of the patient's isolate had features characteristic of extraintestinal pathogenic E. coli and genes distantly related to those defining enteropathogenic E. coli.

KEYWORDS:

case report; comparative genomics; hemolysin; type 3 secretion; virulence factors

PMID:
26410828
PMCID:
PMC4622172
DOI:
10.1093/femspd/ftv076
[Indexed for MEDLINE]
Free PMC Article

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