Format

Send to

Choose Destination
Crit Care Clin. 2015 Oct;31(4):633-48. doi: 10.1016/j.ccc.2015.06.002. Epub 2015 Jul 29.

Biomarkers in Acute Kidney Injury.

Author information

1
Section of Nephrology, Department of Medicine, University of Chicago, 5841 South Maryland Avenue, Suite S-504, MC 5100, Chicago, IL 60637, USA.
2
Section of Nephrology, Department of Medicine, University of Chicago, 5841 South Maryland Avenue, Suite S-504, MC 5100, Chicago, IL 60637, USA. Electronic address: jkoyner@uchicago.edu.

Abstract

Acute kidney injury (AKI) is a common and often lethal complication that is also associated with severe morbidity in hospitalized patients. During the last decade, the standardization of AKI diagnostic criteria has helped to facilitate several large-scale investigations of biomarkers of AKI. These studies have led to the international clinical implementation of several biomarkers of renal injury. This review summarizes the results of many of these multicenter investigations and discusses the clinical utility and interpretation of several of these new clinical tests. The merits of combining biomarkers of kidney function is also discussed.

KEYWORDS:

Acute kidney injury; Biomarkers; Mortality; Renal replacement therapy

PMID:
26410134
DOI:
10.1016/j.ccc.2015.06.002
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center