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Clin Infect Dis. 2016 Jan 1;62(1):75-7. doi: 10.1093/cid/civ793. Epub 2015 Sep 25.

Clinical and Microbiological Characteristics of Invasive Group A Streptococcal Infections Before and After Implementation of a Universal Varicella Vaccine Program.

Author information

1
Infectious Diseases Division, Department of Pediatrics, Centre Hospitalo-Universitaire Sainte Justine, Université de Montréal, Québec, Canada.
2
Microbiology Department, Hôpital Robert Debré, Paris, France.
3
Microbiology and Immunology Department, Centre Hospitalo-Universitaire Sainte Justine, Université de Montréal, Québec, Canada.
4
Pediatric Emergency, Centre Hospitalo-Universitaire Nord, Marseille, France.

Abstract

Since the introduction of the varicella vaccine to the routine immunization schedule, we have observed a 70% reduction in the rate of varicella-associated invasive group A streptococcal infections (IGASI). In the mean time, the clinical presentation of IGASI and microbiological characteristics of GAS strains have changed significantly.

KEYWORDS:

invasive streptococcal infection; necrotizing fasciitis; pediatrics; varicella vaccine

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PMID:
26409062
DOI:
10.1093/cid/civ793
[Indexed for MEDLINE]

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