Format

Send to

Choose Destination
Sci Rep. 2015 Sep 23;5:14434. doi: 10.1038/srep14434.

Effects of concurrent caffeine and mobile phone exposure on local target probability processing in the human brain.

Author information

1
Department of Experimental Neurobiology, University of Pécs, Hungary.
2
Translational Neuromodeling Unit (TNU), Institute for Biomedical Engineering, University of Zurich &ETH Zurich, Switzerland.
3
Laboratory for Social and Neural Systems Research, Department of Economics, University of Zürich, Switzerland.
4
Department of Analytical and Environmental Chemistry, University of Pécs, Hungary.
5
Szentágothai Research Centre, University of Pécs, Hungary.
6
National Institute for Radiobiology and Radiohygiene (NIRR), Budapest, Hungary.

Abstract

Millions of people use mobile phones (MP) while drinking coffee or other caffeine containing beverages. Little is known about the potential combined effects of MP irradiation and caffeine on cognitive functions. Here we investigated whether caffeine intake and concurrent exposure to Universal Mobile Telecommunications System (UMTS) MP-like irradiation may interactively influence neuro-cognitive function in an active visual oddball paradigm. In a full factorial experimental design, 25 participants performed a simple visual target detection task while reaction time (RT) and electroencephalogram (EEG) was recorded. Target trials were divided into Low and High probability sets based on target-to-target distance. We analyzed single trial RT and alpha-band power (amplitude) in the pre-target interval. We found that RT was shorter in High vs. Low local probability trials, and caffeine further shortened RT in High probability trials relative to the baseline condition suggesting that caffeine improves the efficiency of implicit short-term memory. Caffeine also decreased pre-target alpha amplitude resulting in higher arousal level. Furthermore, pre-target gamma power positively correlated with RT, which may have facilitated target detection. However, in the present pharmacologically validated study UMTS exposure either alone or in combination with caffeine did not alter RT or pre-stimulus oscillatory brain activity.

PMID:
26395526
PMCID:
PMC4585767
DOI:
10.1038/srep14434
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Nature Publishing Group Icon for PubMed Central
Loading ...
Support Center