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Eur J Epidemiol. 2015 Aug;30(8):661-708. doi: 10.1007/s10654-015-0082-x. Epub 2015 Sep 19.

The Rotterdam Study: 2016 objectives and design update.

Author information

1
Department of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands. a.hofman@erasmusmc.nl.
2
Department of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
3
Department of Pulmonary Diseases, Erasmus Medical Center, Rotterdam, The Netherlands.
4
Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
5
Department of Gastro-Enterology, Erasmus Medical Center, Rotterdam, The Netherlands.
6
Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands.
7
Department of Otolaryngology, Erasmus Medical Center, Rotterdam, The Netherlands.
8
Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands.
9
Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands.
10
Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands.
11
Department of Dermatology, Erasmus Medical Center, Rotterdam, The Netherlands.
12
Department of Psychiatry, Erasmus Medical Center, Rotterdam, The Netherlands.

Abstract

The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic, neurological, ophthalmic, psychiatric, dermatological, otolaryngological, locomotor, and respiratory diseases. As of 2008, 14,926 subjects aged 45 years or over comprise the Rotterdam Study cohort. The findings of the Rotterdam Study have been presented in over 1200 research articles and reports (see www.erasmus-epidemiology.nl/rotterdamstudy ). This article gives the rationale of the study and its design. It also presents a summary of the major findings and an update of the objectives and methods.

KEYWORDS:

Biomarkers; Cardiovascular diseases; Cohort study; Dermatological diseases; Endocrine diseases; Epidemiologic methods; Genetic epidemiology; Liver diseases; Neurological diseases; Oncology; Ophthalmic diseases; Otolaryngological diseases; Pharmacoepidemiology; Psychiatric diseases; Renal diseases; Respiratory diseases

PMID:
26386597
PMCID:
PMC4579264
DOI:
10.1007/s10654-015-0082-x
[Indexed for MEDLINE]
Free PMC Article

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