A case series of pregnancy- and lactation-associated osteoporosis and a review of the literature

Ther Clin Risk Manag. 2015 Sep 7:11:1361-5. doi: 10.2147/TCRM.S87274. eCollection 2015.

Abstract

The syndrome of pregnancy- and lactation-associated osteoporosis is a rare disorder whose precise etiology and treatment are largely unknown. We herein report two such cases occurring in the early postpartum period that led to multiple fragility compression fractures. Combination therapy of vitamin D and vitamin K enabled a marked gradual increase in bone mineral density.

Keywords: bone mineral density; fracture; vitamin D; vitamin K.