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J Coll Physicians Surg Pak. 2015 Sep;25(9):699-701. doi: 09.2015/JCPSP.699701.

The Role of Intraarticular Platelet Rich Plasma (PRP) Injection in Patients with Internal Knee Derangements.

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Department of Rehabilitation Medicine, Combined Military Hospital, Panoaqil.
Department of Dermatology, Combined Military Hospital, Panoaqil.
Department of Orthopaedic Surgery, Wah Medical College, Wah Cantt.
Department of Rehabilitation Medicine, Armed Forces Institute of Rehabilitation Medicine, Rawalpindi.
Department of Paediatrics, Combined Military Hospital, Panoaqil.


Platelet Rich Plasma (PRP) is an emerging biotechnology which uses patient's own blood components to create healing effect to their own injured tissues. This study was carried out to evaluate the clinical effects, adverse reactions and patient satisfaction after intraarticular injection of platelet rich plasma in a small group of patients with internal derangements of knee at Combined Military Hospital, Panoaqil, Pakistan. In this single center, open study, 10 patients with internal derangements of knee fulfilling the inclusion criteria received two doses of 3 ml of platelet rich plasma as intraarticular knee injection at two weeks interval. All patients were evaluated at 0, 4 and 12 weeks after treatment using IKDC, TEGNER, KOOS and VAS. Adverse events and patient's satisfaction was recorded. There was significant improvement in all scores. Intraarticular PRP injection is safe and effective method in the conservative treatment of internal knee derangements.

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