Format

Send to

Choose Destination
Scand Cardiovasc J. 2015;49(6):308-15. doi: 10.3109/14017431.2015.1086813. Epub 2015 Sep 12.

Heart and Brain Interactions--the Akershus Cardiac Examination (ACE) 1950 Study Design.

Author information

1
a Department of Medical Research , Baerum Hospital, Vestre Viken Hospital Trust , Norway.
2
c Institute of Clinical Medicine, University of Oslo , Oslo , Norway.
3
b Division of Medicine, Akershus University Hospital , Lørenskog , Norway.

Abstract

OBJECTIVES:

The aim of the Akershus Cardiac Examination (ACE) 1950 Study is to investigate the development and progression of cardiovascular and cerebrovascular disease (CVD/CeVD) in an extensively characterized age cohort of middle-aged subjects with longitudinal long-term follow-up.

DESIGN:

The ACE 1950 Study is a prospective, population-based, age-cohort study of all men and women born in 1950 in Akershus County, Norway. The study involves a comprehensive baseline examination, especially for CVD/CeVD, including advanced ultrasound imaging and biobanking ("deep phenotyping"). We expect to obtain an inclusion rate of > 60% from the total study population of 5,827 eligible subjects. Enrollment will be completed during 2015.

CONCLUSIONS:

The ACE 1950 Study will have potential to generate new and relevant insight into identification of subclinical disease progression. Extensive phenotyping will enable identification of novel disease markers and mechanisms for subclinical disease, which can prove important for future disease prevention.

KEYWORDS:

atrial fibrillation; cardiovascular epidemiology; cerebrovascular epidemiology; cognitive function; cohort study; heart failure; stroke

PMID:
26364744
DOI:
10.3109/14017431.2015.1086813
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Taylor & Francis
Loading ...
Support Center