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Curr Opin Biotechnol. 2015 Dec;36:168-75. doi: 10.1016/j.copbio.2015.08.022. Epub 2015 Sep 8.

Top value platform chemicals: bio-based production of organic acids.

Author information

1
Institute of Systems Biotechnology, Universität des Saarlandes, Germany.
2
Institute of Systems Biotechnology, Universität des Saarlandes, Germany. Electronic address: christoph.wittmann@uni-saarland.de.

Abstract

Driven by the quest for sustainability, recent years have seen a tremendous progress in bio-based production routes from renewable raw materials to commercial goods. Particularly, the production of organic acids has crystallized as a competitive and fast-evolving field, related to the broad applicability of organic acids for direct use, as polymer building blocks, and as commodity chemicals. Here, we review recent advances in metabolic engineering and industrial market scenarios with focus on organic acids as top value products from biomass, accessible through fermentation and biotransformation.

PMID:
26360870
DOI:
10.1016/j.copbio.2015.08.022
[Indexed for MEDLINE]

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