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Dermatol Surg. 2015 Oct;41(10):1097-117. doi: 10.1097/DSS.0000000000000486.

Avoiding and Treating Blindness From Fillers: A Review of the World Literature.

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1
Departments of *Dermatology and Skin Science, and †Ophthalmology and Visual Science, University of British Columbia, Vancouver, British Columbia, Canada; ‡Skin Care and Laser Physicians of Beverly Hills; §Division of Dermatology, University of California at Los Angeles, Los Angeles, California.

Abstract

BACKGROUND:

As the popularity of soft tissue fillers increases, so do the reports of adverse events. The most serious complications are vascular in nature and include blindness.

OBJECTIVE:

To review the cases of blindness after filler injection, to highlight key aspects of the vascular anatomy, and to discuss prevention and management strategies.

METHODS:

A literature review was performed to identify all the cases of vision changes from filler in the world literature.

RESULTS:

Ninety-eight cases of vision changes from filler were identified. The sites that were high risk for complications were the glabella (38.8%), nasal region (25.5%), nasolabial fold (13.3%), and forehead (12.2%). Autologous fat (47.9%) was the most common filler type to cause this complication, followed by hyaluronic acid (23.5%). The most common symptoms were immediate vision loss and pain. Most cases of vision loss did not recover. Central nervous system complications were seen in 23.5% of the cases. No treatments were found to be consistently successful in treating blindness.

CONCLUSION:

Although the risk of blindness from fillers is rare, it is critical for injecting physicians to have a firm knowledge of the vascular anatomy and to understand key prevention and management strategies.

PMID:
26356847
DOI:
10.1097/DSS.0000000000000486
[Indexed for MEDLINE]

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