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Acta Cir Bras. 2015 Aug;30(8):580-5. doi: 10.1590/S0102-8650201500800000010.

The Glasgow Prognostic Score. An useful tool to predict survival in patients with advanced esophageal squamous cell carcinoma.

Author information

1
Botucatu Medical School, Universidade Estadual Paulista, BR.
2
Medical School, UNESP, Botucatu, SP, BR.
3
Botucatu Medical School, UNESP, Botucatu, SP, BR.
4
Department of Pathology, Botucatu Medical School, UNESP, Botucatu, SP, BR.

Abstract

PURPOSE:

To evaluate the usefulness of the Glasgow Prognostic Score (GPS) in patients with esophageal carcinoma (EC).

METHODS:

A total of 50 patients with EC were analyzed for GPS, nutritional and clinicopathologic parameters. Patients with CRP ≤ 1.0mg/L and albumin ≥ 3.5mg/L were considered as GPS = 0. Patients with only CRP increased or albumin decreased were classified as GPS = 1 and patients with CRP > 1.0mg/L and albumin < 3.5mg/L were considered as GPS = 2.

RESULTS:

GPS of 0, 1 and 2 were observed in seven, 23 and 20 patients, respectively. A significant inverse relationship was observed between GPS scores and the survival rate. The survival rate was greatest in patients with GPS = 0 and significantly higher than those from patients with GPS = 1 and GPS = 2. Minimum 12-month survival was observed in 71% patients with GPS = 0 and in 30% patients with GPS = 1. None of the patients with GPS = 2 survived for 12 months. A significant relationship between CRP or albumin individually and the survival rate was observed. No significant relationship among nutritional, clinic pathological parameters and survival was found.

CONCLUSION:

Glasgow Prognostic Score is an useful tool to predict survival in patients with esophageal carcinoma.

[Indexed for MEDLINE]
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