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PLoS One. 2015 Sep 9;10(9):e0137165. doi: 10.1371/journal.pone.0137165. eCollection 2015.

Ultra-High-Resolution Computed Tomography of the Lung: Image Quality of a Prototype Scanner.

Author information

1
Division of Cancer Screening, National Cancer Center, Research Center for Cancer Prevention and Screening, Chuo-ku, Tokyo, Japan; Department of Radiology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.
2
Division of Cancer Screening, National Cancer Center, Research Center for Cancer Prevention and Screening, Chuo-ku, Tokyo, Japan.
3
Department of Radiology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.
4
Department of Radiology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan; Department of Radiology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.
5
Department of Radiology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.
6
Department of Endoscopy, Respiratory Endoscopy Division, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.
7
Division of Pathology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.
8
Department of Thoracic Surgery, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.
9
Department of CT Systems Division, Toshiba Medical Systems Corporation, Otawara, Tochigi, Japan.
10
Department of Clinical Oncology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Nagasaki, Japan.
11
Department of Diagnostic Radiology, Hiroshima University, Institute and Graduate School of Biomedical Sciences, Hiroshima, Hiroshima, Japan.
12
Department of Radiology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
13
Department of Radiology, Niigata University Medical and Dental Hospital, Niigata, Niigata, Japan.
14
Department of Radiology, Niigata Cancer Center Hospital, Niigata, Niigata, Japan.
15
Department of Radiology, Ohara General Hospital, Fukushima, Fukushima, Japan.
16
Department of Diagnostic Radiology, Kumamoto University, Faculty of Life Sciences, Kumamoto, Kumamoto, Japan.
17
Department of Radiology, National Hospital Organization Okinawa National Hospital, Ginowan, Okinawa, Japan.

Abstract

PURPOSE:

The image noise and image quality of a prototype ultra-high-resolution computed tomography (U-HRCT) scanner was evaluated and compared with those of conventional high-resolution CT (C-HRCT) scanners.

MATERIALS AND METHODS:

This study was approved by the institutional review board. A U-HRCT scanner prototype with 0.25 mm x 4 rows and operating at 120 mAs was used. The C-HRCT images were obtained using a 0.5 mm x 16 or 0.5 mm x 64 detector-row CT scanner operating at 150 mAs. Images from both scanners were reconstructed at 0.1-mm intervals; the slice thickness was 0.25 mm for the U-HRCT scanner and 0.5 mm for the C-HRCT scanners. For both scanners, the display field of view was 80 mm. The image noise of each scanner was evaluated using a phantom. U-HRCT and C-HRCT images of 53 images selected from 37 lung nodules were then observed and graded using a 5-point score by 10 board-certified thoracic radiologists. The images were presented to the observers randomly and in a blinded manner.

RESULTS:

The image noise for U-HRCT (100.87 ± 0.51 Hounsfield units [HU]) was greater than that for C-HRCT (40.41 ± 0.52 HU; P < .0001). The image quality of U-HRCT was graded as superior to that of C-HRCT (P < .0001) for all of the following parameters that were examined: margins of subsolid and solid nodules, edges of solid components and pulmonary vessels in subsolid nodules, air bronchograms, pleural indentations, margins of pulmonary vessels, edges of bronchi, and interlobar fissures.

CONCLUSION:

Despite a larger image noise, the prototype U-HRCT scanner had a significantly better image quality than the C-HRCT scanners.

PMID:
26352144
PMCID:
PMC4564227
DOI:
10.1371/journal.pone.0137165
[Indexed for MEDLINE]
Free PMC Article

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