Format

Send to

Choose Destination
Am J Ind Med. 2015 Nov;58(11):1138-49. doi: 10.1002/ajim.22527. Epub 2015 Sep 9.

Isocyanates and work-related asthma: Findings from California, Massachusetts, Michigan, and New Jersey, 1993-2008.

Author information

1
Environmental & Occupational Health Surveillance Program, New Jersey Department of Health, Trenton, New Jersey.
2
Occupational Health Surveillance Program, Massachusetts Department of Public Health, Boston, Massachusetts.
3
Occupational Health Branch, California Department of Public Health, Richmond, California.
4
Public Health Institute, Contractor to California Department of Public Health, Richmond, California.
5
Division of Occupational and Environmental Medicine, Michigan State University, East Lansing, Michigan.
6
Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia.
7
University of Pittsburgh Graduate School of Public Health, Department of Epidemiology, Pittsburgh, Pennsylvania.

Abstract

BACKGROUND:

Isocyanates remain a leading cause of work-related asthma (WRA).

METHODS:

Two independent data systems were analyzed for the period 1993-2008: (1) State-based WRA case surveillance data on persons with isocyanate-induced WRA from four states, and (2) Occupational Safety and Health Administration (OSHA) Integrated Management Information System (IMIS) isocyanate air sampling results.

RESULTS:

We identified 368 cases of isocyanate-induced WRA from 32 industries and 678 OSHA isocyanate air samples with detectable levels from 31 industries. Seventeen industries were unique to one or the other dataset.

CONCLUSION:

Isocyanate-induced WRA continues to occur in a wide variety of industries. Two data systems uncovered industries with isocyanate exposures and/or illness. Improved control measures and standards, including medical surveillance, are needed. More emphasis is needed on task-specific guidance, spill clean-up procedures, skin and respiratory protection, and targeted medical monitoring to mitigate the hazards of isocyanate use.

KEYWORDS:

isocyanates; occupational disease prevention; occupational health surveillance; work-related asthma

PMID:
26351141
PMCID:
PMC4697263
DOI:
10.1002/ajim.22527
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Wiley Icon for PubMed Central
Loading ...
Support Center