Format

Send to

Choose Destination
JAMA. 2015 Sep 8;314(10):1052-62. doi: 10.1001/jama.2015.9536.

Diabetes: Advances in Diagnosis and Treatment.

Author information

1
Diabetes Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

Erratum in

Abstract

IMPORTANCE:

Chronic diseases have overtaken acute diseases, such as infections, as the major cause of premature mortality worldwide. Diabetes mellitus, a chronic degenerative metabolic disease, has reached epidemic proportions in the past 30 years, with worldwide prevalence approaching 400 million people.

OBSERVATIONS AND ADVANCES:

The epidemic is largely secondary to an increasing sedentary lifestyle and highly prevalent overweight and obesity contributing to the development of type 2 diabetes. Clinical research efforts have developed and demonstrated effective strategies for prevention, and the annual incidence of diabetes in the United States may be decreasing for the first time in 3 decades. The long-term complications of diabetes cause severe morbidity and mortality. Here too the means of reducing the burden of microvascular and cardiovascular disease have been proved.

CONCLUSIONS AND RELEVANCE:

Improved glycemic control and better management of other identified risk factors for the complications of diabetes and more effective treatment of cardiovascular disease and microvascular complications have resulted in a more optimistic outlook for people with diabetes. This review focuses on recent advances in diagnosis and management and the remaining challenges in the prevention and treatment of diabetes mellitus.

PMID:
26348754
DOI:
10.1001/jama.2015.9536
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Silverchair Information Systems
Loading ...
Support Center