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Br J Nutr. 2015 Nov 14;114(9):1341-59. doi: 10.1017/S0007114515003177. Epub 2015 Sep 7.

Dietary patterns and CVD: a systematic review and meta-analysis of observational studies.

Author information

1
1Blanquerna School of Health Science, Facultat de Ciències de la Salut Blanquerna,Universitat Ramon Llull,Barcelona 08025,Spain.
2
2Research Support Unit for Tarragona-Reus,Institut Universitari d'Investigació en Atenció Primària Jordi Gol (IDIAP Jordi Gol),43202 Tarragona,Spain.

Abstract

Epidemiological studies show that diet is linked to the risk of developing CVD. The objective of this meta-analysis was to estimate the association between empirically derived dietary patterns and CVD. PubMed was searched for observational studies of data-driven dietary patterns that reported outcomes of cardiovascular events. The association between dietary patterns and CVD was estimated using a random-effects meta-analysis with 95 % CI. Totally, twenty-two observational studies met the inclusion criteria. The pooled relative risk (RR) for CVD, CHD and stroke in a comparison of the highest to the lowest category of prudent/healthy dietary patterns in cohort studies was 0·69 (95% CI 0·60, 0·78; I 2=0%), 0·83 (95% CI 0·75, 0·92; I 2=44·6%) and 0·86 (95% CI 0·74, 1·01; I 2=59·5%), respectively. The pooled RR of CHD in a case-control comparison of the highest to the lowest category of prudent/healthy dietary patterns was 0·71 (95% CI 0·63, 0·80; I 2=0%). The pooled RR for CVD, CHD and stroke in a comparison of the highest to the lowest category of western dietary patterns in cohort studies was 1·14 (95% CI 0·92, 1·42; I 2=56·9%), 1·03 (95% CI 0·90, 1·17; I 2=59·4%) and 1·05 (95% CI 0·91, 1·22; I 2=27·6%), respectively; in case-control studies, there was evidence of increased CHD risk. Our results support the evidence of the prudent/healthy pattern as a protective factor for CVD.

KEYWORDS:

CVD; Dietary patterns; Meta-analyses; RR relative risk; Systematic reviews

PMID:
26344504
DOI:
10.1017/S0007114515003177
[Indexed for MEDLINE]

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