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Med Ultrason. 2015 Sep;17(3):322-6. doi: 10.11152/mu.2013.2066.173.khu.

The role of shear wave elastography in the diagnosis of chronic autoimmune thyroiditis.

Author information

1
Department of Radiology, Baskent University, School of Medicine, Ankara, Turkey. korayhekim@yahoo.com.tr.
2
Department of Radiology, Baskent University, School of Medicine, Ankara, Turkey.
3
Department of Endocrinology, Baskent University, School of Medicine, Ankara, Turkey.
4
Department of Biostatistics, Baskent University, School of Medicine, Ankara, Turkey.

Abstract

AIMS:

The aim of this study is to assess the applicability of shear wave elastography (SWE) in the diagnosis of chronic autoimmune thyroiditis (CAT) patients.

MATERIAL AND METHODS:

The study group consisted of 50 patients with first-diagnosed CAT and 40 control subjects (CS). In all patients with CAT and CS, sonoelastographic measurements were made in both thyroid lobes. Optimal cut-off values were chosen to maximize the sum of sensitivity and specificity. Positive predictive value (PPV), negative predictive value (NPV), and accuracy values were also calculated.

RESULTS:

Quantitative elastographic analysis evaluated by SWE in CAT patients (2.56 +/- 0.30 m/s) was significantly higher compared with CS (1.63 +/- 0.12 m/s) (p<0.001). The optimal cut-off value was 2.42 m/s. SWE had 77% sensitivity, 71% specificity, 92% PPV, 81% NPV, and 87% accuracy for the presence of CAT.

CONCLUSIONS:

Our data indicate that SWE correctly defines the elasticity of thyroid parenchyma, and this technique may assist in the diagnosis and treatment monitoring of CAT.

PMID:
26343080
DOI:
10.11152/mu.2013.2066.173.khu
[Indexed for MEDLINE]
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