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Gac Sanit. 2015 Nov-Dec;29(6):464-71. doi: 10.1016/j.gaceta.2015.07.002. Epub 2015 Sep 2.

[Interval cancers and episode sensitivity in population-based screening programmes for colorectal cancer: a systematic review].

[Article in Spanish]

Author information

1
Prevención y Control del Cáncer, Instituto Catalán de Oncología-IDIBELL, L'Hospitalet de Llobregat, Barcelona, España.
2
Prevención y Control del Cáncer, Instituto Catalán de Oncología-IDIBELL, L'Hospitalet de Llobregat, Barcelona, España. Electronic address: mgarcia@iconcologia.net.
3
Prevención y Control del Cáncer, Instituto Catalán de Oncología-IDIBELL, L'Hospitalet de Llobregat, Barcelona, España; Departamento de Enfermería Fundamental y Médico-Quirúrgica, Universidad de Barcelona, L'Hospitalet de Llobregat, Barcelona, España.
4
Prevención y Control del Cáncer, Instituto Catalán de Oncología-IDIBELL, L'Hospitalet de Llobregat, Barcelona, España; CIBER de Epidemiología y Salud Pública (CIBERESP), España.
5
Prevención y Control del Cáncer, Instituto Catalán de Oncología-IDIBELL, L'Hospitalet de Llobregat, Barcelona, España; CIBER de Epidemiología y Salud Pública (CIBERESP), España; Departamento de Ciencias Clínicas, Universidad de Barcelona, L'Hospitalet de Llobregat, Barcelona, España.

Abstract

OBJECTIVE:

To describe interval cancers (IC) and the sensitivity of colorectal cancer (CRC) screening programmes.

METHODS:

A systematic review of the literature was conducted through a MEDLINE (PubMed) search. The search strategy combined the terms 'interval cancer', 'false negative', 'mass screening', 'screening' 'early detection of cancer', 'colorectal cancer' and 'bowel cancer'. Inclusion criteria consisted of population-based screening programmes, original articles written in English or Spanish and publication dates between 1999/01/01 and 2015/02/28. A narrative synthesis of the included articles was performed detailing the characteristics of the screening programmes, the IC rate, and the information sources used in each study.

RESULTS:

Thirteen articles were included. The episode sensitivity of CRC screening programmes ranged from 42.2% to 65.3% in programmes using the guaiac test and between 59.1% and 87.0% with the immunochemical test. We found a higher proportion of women who were diagnosed with IC and these lesions were mainly located in the proximal colon.

CONCLUSION:

There is wide variability in the IC rate in CRC programmes. To ensure comparability between programmes, there is a need for consensus on the working definition of IC and the methods used for their identification and quantification.

KEYWORDS:

Adverse effects; Colorectal neoplasms; Cribado; Cáncer de intervalo; Efectos adversos; Interval cancer; Mass screening; Neoplasias colorrectales

PMID:
26341155
DOI:
10.1016/j.gaceta.2015.07.002
[Indexed for MEDLINE]
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