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Eur Heart J. 2016 Jan 7;37(2):152-60. doi: 10.1093/eurheartj/ehv437. Epub 2015 Sep 1.

EURObservational Research Programme: the Chronic Ischaemic Cardiovascular Disease Registry: Pilot phase (CICD-PILOT).

Author information

1
Department of Cardiology, Pitié-Salpêtrière Hospital, University Pierre and Marie Curie and IHU ICAN, Paris, France michel.komajda@psl.aphp.fr.
2
2nd Medical Department with Cardiology and Intensive Care Medicine, Rudolfstiftung Hospital, Vienna, Austria.
3
Department of Cardiology, Pitié-Salpêtrière Hospital, University Pierre and Marie Curie and IHU ICAN, Paris, France.
4
Cardiology Unit, Department of Medicine, Solna, Karolinska University Hospital, Stockholm, Sweden.
5
GVM Care and Research, Maria Cecilia Hospital, Cotignola, Italy.
6
Department of Cardiology and LTTA Centre, University Hospital of Ferrara and Maria Cecilia Hospital, GVM Care and Research, E.S. Health Science Foundation, Cotignola, Italy.
7
Centre Cardiologique et Vasculaire, Thionville, France.
8
DHU FIRE, Université Paris-Diderot, Hôpital Bichat, AP-HP, and INSERM, Paris U-1148, France.
9
Maria Cecilia Hospital, GVM Care and Research, Ettore Sansavini Health Science Foundation, Cotignola, Italy.
10
Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands.
11
2nd Department of Coronary Artery Disease, Institute of Cardiology, Warsaw, Poland.
12
Department of Cardiology, Ca' Foncello Hospital, Treviso, Italy.
13
Department of Cardiology, University Hospital, Lille, France.
14
Cardiac Arrhythmias Department, Almazov Research Institute of Cardiology, Saint-Petersburg, Russia.
15
Latvian Center of Cardiology, Pauls Stradins Clinical University Hospital, Riga, Latvia.
16
Department of Cardiology, Hospital of the Lithuanian Health Science University, Kaunas, Lithuania.
17
Medizinische Klinik I, Klinikum Fuerth, Fürth, Germany.
18
Cardiology Department, Hospital De Santa Cruz, Centro Hospitalar De Lisboa Ocidental, Carnaxide, Portugal.
19
1st University Cardiology Clinic, Hippocratio Hospital, Athens, Greece.
20
Department of Cardiology, Monza Hospital Centru Cardiovascular, Bucharest, Romania.
21
EURObservational Research Programme, European Society of Cardiology, Sophia-Antipolis, France.

Abstract

AIMS:

Chronic ischaemic cardiovascular disease (CICD) is a major cause of mortality and morbidity worldwide. The primary objective of the CICD-Pilot registry was to describe the clinical characteristics and management modalities across Europe in a broad spectrum of patients with CICD.

METHODS AND RESULTS:

The CICD-Pilot registry is an international prospective observational longitudinal registry, conducted in 100 centres from 10 countries selected to reflect the diversity of health systems and care attitudes across Europe. From April 2013 to December 2014, 2420 consecutive CICD patients with non-ST-elevation acute coronary syndrome (n = 755) and chronic stable coronary artery disease (n = 1464), of whom 933 (63.7%) were planned for elective coronary intervention, or with peripheral artery disease (PAD) (n = 201), were enrolled (30.5% female patients). Mean age was 66.6 ± 10.9 years. The following risk factors were reported: smoking 54.6%, diabetes mellitus 29.2%, hypertension 82.6%, and hypercholesterolaemia 74.1%. Assessment of cardiac function was made in 69.5% and an exercise stress test in 21.2% during/within 1 year preceding admission. New stress imaging modalities were applied in a minority of patients. A marked increase was observed at discharge in the rate of prescription of angiotensin-converting enzyme-inhibitors/angiotensin receptor blockers (82.8%), beta-blockers (80.2%), statins (92.7%), aspirin (90.3%), and clopidogrel (66.8%). Marked differences in clinical profile and treatment modalities were observed across the four cohorts.

CONCLUSION:

The CICD-Pilot registry suggests that implementation of guideline-recommended therapies has improved since the previous surveys but that important heterogeneity exists in the clinical profile and treatment modalities in the different cohorts of patients enrolled with a broad spectrum of CICDs.

KEYWORDS:

Cardiac procedures; Drug therapy; Ischaemic cardiovascular disease; Management; Stable angina

PMID:
26330421
DOI:
10.1093/eurheartj/ehv437
[Indexed for MEDLINE]

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