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Am J Clin Dermatol. 2015 Dec;16(6):463-74. doi: 10.1007/s40257-015-0153-5.

Alternative Systemic Treatments for Vitiligo: A Review.

Author information

1
The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, 240 East 38th Street, New York, NY, 10016, USA.
2
The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, 240 East 38th Street, New York, NY, 10016, USA. seth.orlow@nyumc.org.

Abstract

Vitiligo is a common, acquired disorder of skin pigmentation that can significantly impact quality of life. It often represents a therapeutic challenge, which has resulted in interest in alternative treatments such as herbal and vitamin supplements. In this review, we provide an overview of the most commonly studied complementary agents, describe proposed mechanisms of action, identify potential adverse effects, and discuss the primary evidence supporting their use. Our discussion focuses on L-phenylalanine, Polypodium leucotomos, khellin, Ginkgo biloba, and vitamins and minerals, including vitamins B12, C, and E, folic acid, and zinc used as monotherapy or in combination with other treatments for the management of vitiligo.

PMID:
26329814
DOI:
10.1007/s40257-015-0153-5
[Indexed for MEDLINE]

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