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Soft Matter. 2015 Oct 21;11(39):7707-11. doi: 10.1039/c5sm01490e. Epub 2015 Sep 1.

Grafted biomembranes containing membrane proteins--the case of the leucine transporter.

Author information

1
Department of Chemistry and Nano-Science Center, University of Copenhagen, Universitetsparken 5, DK 2100, Copenhagen, Denmark. cardenas@nano.ku.dk.

Abstract

Here, we bind the sodium dependent amino acid transporter on nitrilotriacetic acid/polyethylene glycol functionalized gold sensors in detergents and perform a detergent-lipid exchange with phosphatidylcholine. We characterize the LeuT structure in the adsorbed film by magnetic contrast neutron reflection using the predicted model from molecular dynamic simulations.

PMID:
26325086
DOI:
10.1039/c5sm01490e
[Indexed for MEDLINE]

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