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J Clin Neurosci. 2016 Jan;23:95-100. doi: 10.1016/j.jocn.2015.05.041. Epub 2015 Aug 28.

Overall outcomes following early interventions for intracranial arteriovenous malformations with hematomas.

Author information

1
Department of Neurosurgery, Louisiana State University Health Shreveport, 1501 Kings Highway, Shreveport, LA 71130-3932, USA.
2
Department of Neurosurgery, Louisiana State University Health Shreveport, 1501 Kings Highway, Shreveport, LA 71130-3932, USA. Electronic address: ananda@lsuhsc.edu.

Abstract

We evaluated the timing and predictors of surgical intervention for intracranial arteriovenous malformations (AVM) with hematoma. A ruptured intracranial AVM with hematoma is an emergency condition, and the optimal timing for surgical intervention is not well understood. In addition, the outcome predictors of surgical intervention have rarely been reported. We identified and analyzed 78 patients treated with microsurgical resection for pathologically proven AVM at Louisiana State University Health in Shreveport from February 1992 to December 2004. All 78 patients were diagnosed with ruptured AVM before surgery. The independent variables, including patient demographics, timing of surgery, location of the AVM and comorbidities were analyzed to assess outcome. The results of this series revealed that surgical intervention after 48hours resulted in poor outcomes for patients with hematoma, following a ruptured AVM. Several other prognostic factors, including younger age (11-40years), Spetzler-Martin Grade I and II, and AVM in a supratentorial location, had significant positive effects on outcomes. However, hypertension, smoking, and a prior embolization showed significant negative effects on outcomes after surgery. The multiple logistic regression analyses also revealed that the timing of surgical intervention had a significant effect on outcomes in patients with hematoma following ruptured AVM. Early intervention is the key to success in these patients.

KEYWORDS:

Early surgical intervention; Intracranial arteriovenous malformation; Outcomes; Predictors

PMID:
26321303
DOI:
10.1016/j.jocn.2015.05.041
[Indexed for MEDLINE]

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