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J Biotechnol. 2015 Dec 20;216:140-1. doi: 10.1016/j.jbiotec.2015.08.009. Epub 2015 Aug 28.

Complete genome sequence of Streptomyces sp. CNQ-509, a prolific producer of meroterpenoid chemistry.

Author information

1
Technology Platform Genomics, Center for Biotechnology, Bielefeld University, Bielefeld, Germany.
2
Pharmaceutical Institute, Tübingen University, Tübingen, Germany; German Centre for Infection Research (DZIF), Partner Site Tübingen, Germany.
3
Pharmaceutical Institute, Tübingen University, Tübingen, Germany.
4
Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA.
5
Pharmaceutical Institute, Tübingen University, Tübingen, Germany; German Centre for Infection Research (DZIF), Partner Site Tübingen, Germany. Electronic address: leonard.kaysser@uni-tuebingen.de.

Abstract

Streptomyces sp. CNQ-509 is a marine actinomycete belonging to the MAR4 streptomycete lineage. MAR4 strains have been linked to the production of diverse and otherwise rare meroterpenoid compounds. The genome sequence of Streptomyces sp. CNQ-509 was found to contain 29 putative gene clusters for the biosynthesis of secondary metabolites, some of them potentially involved in the formation of meroterpenoid molecules.

KEYWORDS:

Genome; MAR4; Meroterpenoids; Streptomyces

PMID:
26319318
DOI:
10.1016/j.jbiotec.2015.08.009
[Indexed for MEDLINE]

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