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FEMS Microbiol Immunol. 1989 Jun;1(6-7):407-9.

Lewis a blood group antigen of non-secretors: a receptor for candida blastospores.

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Department of Bacteriology, Medical School, University of Edinburgh, U.K.


This study tested the hypothesis that the Lewis a blood group antigen found predominantly on the cells of non-secretors might be one of the receptors for Candida species. Binding of strain 3118C to epithelial cells from either secretor or non-secretor donors was not inhibited by treating the cells with anti-Lewis a or anti-Lewis b antisera. Binding of strain 3091 to non-secretor cells was inhibited by pretreating the cells with anti-Lewis a, but this was not observed for secretor cells. The results suggest that Lewis a might be one of the receptors for some yeast strains.

[Indexed for MEDLINE]

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