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Cell. 2015 Aug 27;162(5):1170-1170.e1. doi: 10.1016/j.cell.2015.08.029.

SnapShot: Astrocytes in Health and Disease.

Author information

1
Department of Neurobiology, Stanford University, Stanford, CA 94305, USA; Department of Pharmacology and Therapeutics, The University of Melbourne, Melbourne, Victoria 3010, Australia.
2
Department of Neurobiology, Stanford University, Stanford, CA 94305, USA.

Abstract

Astrocytes are central nervous system (CNS) glial cells with many important functions for normal development and neural functioning. They help control extracellular ion and neurotransmitter concentrations; provide neurotrophic support; are implicated in synapse formation, function, and pruning; and help maintain the blood-brain barrier. Following injury and in disease, they undergo rapid and chronic alterations in function that can either promote or hinder recovery, depending on the disease.

PMID:
26317476
DOI:
10.1016/j.cell.2015.08.029
[Indexed for MEDLINE]
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