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J Biomark. 2013;2013:378790. doi: 10.1155/2013/378790. Epub 2013 Dec 17.

Markers of Oxidative Stress during Diabetes Mellitus.

Author information

1
Department of Biochemistry & Biochemical Engineering, Sam Higginbotom Institute of Agriculture, Technology & Sciences, Allahabad 211007, India.
2
Department of Biochemistry, University of Allahabad, Allahabad 211002, India.
3
Department of Biochemistry & Biochemical Engineering, Sam Higginbotom Institute of Agriculture, Technology & Sciences, Allahabad 211007, India ; Department of Biochemistry, University of Allahabad, Allahabad 211002, India.

Abstract

The prevalence of diabetes mellitus is rising all over the world. Uncontrolled state of hyperglycemia due to defects in insulin secretion/action leads to a variety of complications including peripheral vascular diseases, nephropathy, neuropathy, retinopathy, morbidity, and/or mortality. Large body of evidence suggests major role of reactive oxygen species/oxidative stress in development and progression of diabetic complications. In the present paper, we have discussed the recent researches on the biomarkers of oxidative stress during type 2 diabetes mellitus.

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