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Vasc Health Risk Manag. 2015 Aug 17;11:451-9. doi: 10.2147/VHRM.S83718. eCollection 2015.

Assessing the risk of recurrent venous thromboembolism--a practical approach.

Author information

1
Division of Angiology, Medical University Clinic, Kantonsspital Aarau AG, Aarau, Switzerland.
2
Clinic for Angiology, University Hospital, University of Zurich, Z├╝rich, Switzerland.
3
Clinic for Angiology Oberaargau, Langenthal, Switzerland.

Abstract

Recurrent venous thromboembolism (VTE) is associated with increased morbidity and mortality. This risk is lowered by anticoagulation, with a large effect in the initial phase following the venous thromboembolic event, and with a smaller effect in terms of secondary prevention of recurrence when extended anticoagulation is performed. On the other hand, extended anticoagulation is associated with an increased risk of major bleeding and thus leads to morbidity and mortality. Therefore, it is necessary to assess the risk of recurrence for VTE on an individual basis, and a recommendation for secondary prophylaxis should be specifically based on risk calculation of recurrence of VTE and bleeding. In this review, we provide a comprehensive summary of relevant risk factors for recurrent VTE and a practical approach for assessing the risk of recurrence in daily practice.

KEYWORDS:

hemorrhage; risk assessment; thrombosis

PMID:
26316770
PMCID:
PMC4544622
DOI:
10.2147/VHRM.S83718
[Indexed for MEDLINE]
Free PMC Article

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