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J Clin Microbiol. 2015 Nov;53(11):3639-45. doi: 10.1128/JCM.01985-15. Epub 2015 Aug 26.

Clinical Characteristics, Laboratory Identification, and In Vitro Antifungal Susceptibility of Yarrowia (Candida) lipolytica Isolates Causing Fungemia: a Multicenter, Prospective Surveillance Study.

Author information

1
Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
2
State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong Department of Microbiology, The University of Hong Kong, Hong Kong Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong.
3
Department of Microbiology, The University of Hong Kong, Hong Kong.
4
Department of Microbiology, the First Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, China.
5
Department of Clinical Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
6
Division of Clinical Microbiology, Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
7
Laboratory Center, General Hospital of Tianjin Medical University, Tianjin, China.
8
State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong.
9
Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China xycpumch@139.com pcywoo@hku.hk.
10
State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong Department of Microbiology, The University of Hong Kong, Hong Kong Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong xycpumch@139.com pcywoo@hku.hk.

Abstract

Our case series showed that uncomplicated Yarrowia lipolytica fungemia might be treated with catheter removal alone. The Vitek 2 YST identification (ID) card system, matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS), and internal transcribed spacer and 25S nuclear ribosomal DNA (nrDNA) gene sequencing provided reliable identification. All isolates had low MICs to voriconazole, echinocandins, and amphotericin B.

PMID:
26311865
PMCID:
PMC4609733
DOI:
10.1128/JCM.01985-15
[Indexed for MEDLINE]
Free PMC Article

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