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Neuroimage. 2016 Jan 1;124(Pt B):1238-41. doi: 10.1016/j.neuroimage.2015.08.043. Epub 2015 Aug 24.

Connected brains and minds--The UMCD repository for brain connectivity matrices.

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Memory and Aging Center, Department of Neurology, University of California, San Francisco, CA, USA. Electronic address:
Laboratory of Neuroimaging, Department of Neurology, University of Southern California, Los Angeles, CA, USA.


We describe the USC Multimodal Connectivity Database (, an interactive web-based platform for brain connectivity matrix sharing and analysis. The site enables users to download connectivity matrices shared by other users, upload matrices from their own published studies, or select a specific matrix and perform a real-time graph theory-based analysis and visualization of network properties. The data shared on the site span a broad spectrum of functional and structural brain connectivity information from humans across the entire age range (fetal to age 89), representing an array of different neuropsychiatric and neurodegenerative disease populations (autism spectrum disorder, ADHD, and APOE-4 carriers). An analysis combining 7 different datasets shared on the site illustrates the diversity of the data and the potential for yielding deeper insight by assessing new connectivity matrices with respect to population-wide network properties represented in the UMCD.

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