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Cancer Epidemiol Biomarkers Prev. 2015 Sep;24(9):1388-97. doi: 10.1158/1055-9965.EPI-15-0060.

Prevalence, Long-term Development, and Predictors of Psychosocial Consequences of False-Positive Mammography among Women Attending Population-Based Screening.

Author information

1
Department of Medical Imaging and Physiology, Skåne University Hospital Malmö, Malmö, Sweden. anetta.bolejko@skane.se.
2
The PRO-CARE Group, School of Health and Society, Kristianstad University, Kristianstad, Sweden.
3
Department of Caring Science, Malmö University, Malmö, Sweden.
4
Department of Medical Imaging and Physiology, Skåne University Hospital Malmö, Malmö, Sweden.

Abstract

BACKGROUND:

Cancer screening aims to detect cancer at an asymptomatic stage, although side effects from screening also occur. We investigated the prevalence, longitudinal development, and predictors of psychosocial consequences of false-positive breast cancer screening.

METHODS:

Three hundred ninety-nine women with false-positive screening mammography responded to the Consequences of Screening-Breast Cancer (COS-BC) questionnaire immediately after a negative diagnosis (free from breast cancer) following recall examination(s) (baseline), and 6 and 12 months later. Age-matched controls (n = 499) with a negative mammogram responded to the COS-BC at the same occasions. Five COS-BC scales (Sense of dejection, Anxiety, Behavioral, Sleep, and Existential values) were used as outcome measures.

RESULTS:

Women with false-positive mammography had consistently higher prevalence of all five consequences compared with controls (P < 0.001). The prevalences decreased between baseline and 6 months (P < 0.001) but were stable between 6 and 12 months (P ≥ 0.136). Early recall profoundly predicted long-term consequences for all five outcomes (OR, 3.05-10.31), along with dissatisfaction with information at recall (OR, 2.28-2.56), being foreign-born (OR, 2.35-3.71), and lack of social support (OR, 1.13-1.25).

CONCLUSION:

This 1-year longitudinal study shows that women experience psychosocial consequences of false-positive screening mammography. Early recall should be performed cautiously, and provision of information as well as social support may reduce psychosocial consequences.

IMPACT:

Although delivery of population-based screening reduces breast cancer mortality, it also raises the issue of its impact on the psychosocial well-being of healthy women. Our findings identify predictors that can be targeted in future efforts to reduce the side effects of mammographic screening.

PMID:
26311562
DOI:
10.1158/1055-9965.EPI-15-0060
[Indexed for MEDLINE]
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