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Prog Mol Biol Transl Sci. 2015;134:25-41. doi: 10.1016/bs.pmbts.2015.04.002. Epub 2015 May 27.

Stem Cells in the Cornea.

Author information

1
Department of Ophthalmology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
2
Department of Ophthalmology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. Electronic address: jlfunder@pitt.edu.

Abstract

The cornea is the tough, transparent tissue through which light first enters the eye and functions as a barrier to debris and infection as well as two-thirds of the refractive power of the eye. Corneal damage that is not promptly treated will often lead to scarring and vision impairment. Due to the limited options currently available to treat corneal scars, the identification and isolation of stem cells in the cornea has received much attention, as they may have potential for autologous, cell-based approaches to the treatment of damaged corneal tissue.

KEYWORDS:

Cornea; Stem cells

PMID:
26310147
PMCID:
PMC5327505
DOI:
10.1016/bs.pmbts.2015.04.002
[Indexed for MEDLINE]
Free PMC Article

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