Format

Send to

Choose Destination
J Laryngol Otol. 2016 Jan;130 Suppl 1:S32-7. doi: 10.1017/S0022215115002212. Epub 2015 Aug 25.

Squamous cell carcinoma of the lip: depth of invasion, local recurrence and regional metastases. Experience of a rural multidisciplinary head and neck unit.

Author information

1
Ear,Nose and Throat Surgical Department,Toowoomba General Hospital,Queensland,Australia.

Abstract

BACKGROUND:

The internationally recognised American Joint Committee on Cancer (tumour-node-metastasis) staging system utilises tumour size to determine stage. Other factors (i.e. tumour depth) may provide additional prognostic information.

METHOD:

A thorough retrospective analysis was performed of 68 patients with primary lip squamous cell carcinoma operated on or discussed by the Darling Downs Health Service between 2005 and 2013.

RESULTS:

Twelve patients developed lymphatic spread. There was a statistically significant increased risk of nodal metastasis in: patients with tumours of increased thickness (U = 103.50; degrees of freedom = 68; p < 0.001), those with a larger overall tumour size (U = 163.50; degrees of freedom = 68; p = 0.005) and patients living further from the treatment centre (U = 199.00; degrees of freedom = 68; p = 0.018).

CONCLUSION:

It may be reasonable that other factors are considered for staging of lip squamous cell carcinomas, in combination with tumour-node-metastasis staging. Depth of invasion may have utility in prognosis and treatment; however, larger prospective analysis needs to be performed. Patients living in a more rural setting presented with more advanced disease, suggesting an ongoing rural-metropolitan gap in healthcare.

KEYWORDS:

Carcinoma; Epidermoid; Lip; Planocellular; Prognosis; Squamous; Squamous Cell Carcinoma

PMID:
26304159
DOI:
10.1017/S0022215115002212
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Cambridge University Press
Loading ...
Support Center