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Ann Hematol. 2015 Nov;94(11):1765-76. doi: 10.1007/s00277-015-2481-1. Epub 2015 Aug 25.

Recommendations for the use of long-term central venous catheter (CVC) in children with hemato-oncological disorders: management of CVC-related occlusion and CVC-related thrombosis. On behalf of the coagulation defects working group and the supportive therapy working group of the Italian Association of Pediatric Hematology and Oncology (AIEOP).

Author information

1
Department of Biomedicine and Human Oncology, Pediatric Unit, University of Bari "Aldo Moro", Bari, Italy.
2
Department of Pediatrics, Hematology Unit, University of Turin, Turin, Italy. paola.saracco@unito.it.
3
Department of Pediatric Hematology Oncology, Bambino Gesù Children Hospital, Rome, Italy.
4
Thrombosis and Hemostasis Unit, Giannina Gaslini Children's Hospital, Genoa, Italy.
5
Pediatric Hematology Oncology and Bone Marrow Unit, Ospedale Infantile Regina Margherita, Turin, Italy.
6
Department of Surgery, General and Thoracic Surgery Unit, Bambino Gesù Children Hospital, Rome, Italy.
7
Pediatric Hematology Oncology Unit, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
8
Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy.

Abstract

Central venous catheters (CVC), used for the management of children with hemato-oncological disorders, are burdened by a significant incidence of mechanical, infective, or thrombotic complications. These complications favor an increasing risk in prolongation of hospitalization, extra costs of care, and sometimes severe life-threatening events. No guidelines for the management of CVC-related occlusion and CVC-related thrombosis are available for children. To this aim, members of the coagulation defects working group and the supportive therapy working group of the Italian Association of Pediatric Hematology and Oncology (AIEOP) reviewed the pediatric and adult literature to propose the first recommendations for the management of CVC-related occlusion and CVC-related thrombosis in children with hemato-oncological disorders.

KEYWORDS:

CVC occlusion; Central venous catheter; Pediatric hematology oncology; Thrombosis

PMID:
26300457
DOI:
10.1007/s00277-015-2481-1
[Indexed for MEDLINE]

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