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Int J Public Health. 2015 Nov;60(7):789-98. doi: 10.1007/s00038-015-0708-5. Epub 2015 Aug 23.

Hepatitis C in key populations in Latin America and the Caribbean: systematic review and meta-analysis.

Author information

1
Pan American Health Organization, HIV/STI/TB and Viral Hepatitis, 525 23rd St NW, Washington, DC, 20037, USA. alonsomon@paho.org.
2
Pan American Health Organization, HIV/STI/TB and Viral Hepatitis, 525 23rd St NW, Washington, DC, 20037, USA.
3
Pan American Health Organization, Knowledge Management, Bioethics and Research, Washington, DC, USA.

Abstract

OBJECTIVES:

Summarize hepatitis C virus (HCV) prevalence in injecting (IDU) and non-injecting drug users (NIDU), men who have sex with men (MSM), sex workers, and prison inmates in Latin America and the Caribbean (LAC).

METHODS:

Systematic review on HCV prevalence in sub-populations in LAC. Databases searched from 1-1-2000 to 10-30-2013.

INCLUSION CRITERIA:

prevalence studies in sub-populations in LAC. HCV-antibody was marker for prevalence of current/past HCV infection and HCV-RNA for prevalence of HCV current infection.

RESULTS:

IDU HCV current/past infection presented highest prevalence, from 1.7 % in Colombia to over 95 % in Ciudad Juarez and Tijuana, Mexico and pooled regional anti-HCV prevalence was 49 % (CI 95 % 22.6-76.3 %). NIDU, MSM and sex workers anti-HCV prevalence was below 10 %, and pooled regional prevalence of 4 % (CI 95 % 2.6-4.5 %), 3 % (CI 95 % 1.7-4.5 %) and 2 % (CI 95 % 1.0-3.4 %), respectively. Prison inmates presented higher values, but prevalence decreased over the 15-year time span (p < 0.001). Current HCV infection from three countries showed prevalence under 10 % in prison inmates and 1-46 % among drug users.

CONCLUSIONS:

Disease burden is high and surveillance, prevention and treatment should target these groups in LAC.

KEYWORDS:

Caribbean; Drug users; Hepatitis C; Latin America; Men who have sex with men; Prisoners

PMID:
26298439
PMCID:
PMC4636523
DOI:
10.1007/s00038-015-0708-5
[Indexed for MEDLINE]
Free PMC Article

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