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Neurobiol Learn Mem. 2015 Nov;125:93-7. doi: 10.1016/j.nlm.2015.08.005. Epub 2015 Aug 19.

How does the hippocampus shape decisions?

Author information

1
VA Boston Healthcare System, 150 South Huntington Ave (151A), Boston, MA 02130, United States; Boston University School of Medicine, Department of Psychiatry, 72 E Concord St, Boston, MA 02118, United States. Electronic address: palombo@bu.edu.
2
Wellesley College, Department of Psychology, 106 Central St, Wellesley, MA 02481, United States; VA Boston Healthcare System, 150 South Huntington Ave (151A), Boston, MA 02130, United States; Boston University School of Medicine, Department of Psychiatry, 72 E Concord St, Boston, MA 02118, United States.
3
VA Boston Healthcare System, 150 South Huntington Ave (151A), Boston, MA 02130, United States; Boston University School of Medicine, Department of Psychiatry, 72 E Concord St, Boston, MA 02118, United States.

Abstract

Making optimal decisions depends on an appreciation of the value of choices. An important source of information about value comes from memory for prior experience. Such value-based learning has historically been considered the domain of a striatal memory system. However, recent developments suggest that memorial representations supported by the hippocampus may also contribute to decision making. Unlike striatal representations, hippocampal ones are flexible; they can be modified and updated as new information is acquired. In this paper we argue that the hippocampus plays a pivotal role in value-based decision making via three flexible learning mechanisms: (1) updating, (2) generalization, and (3) construction.

KEYWORDS:

Decision making; Hippocampus; Value

PMID:
26297967
DOI:
10.1016/j.nlm.2015.08.005
[Indexed for MEDLINE]

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