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Trends Biochem Sci. 1989 Mar;14(3):93-6.

A reappraisal of the binding of cytosolic enzymes to erythrocyte membranes.

Abstract

Several cytosolic proteins have been shown to be associated with hypotonic erythrocyte ghosts via electrostatic interactions with the anion transport band 3 protein. This article considers the problems of demonstrating binding under physiological conditions and reviews the evidence for the relevance of enzyme binding to the membrane for the regulation of glycolysis. The hypotheses for the existence of topological and sequential multienzyme complexes of the glycolytic enzymes in erythrocytes are also discussed.

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PMID:
2629715
DOI:
10.1016/0968-0004(89)90128-x
[Indexed for MEDLINE]

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