Diagnostically Challenging Epithelioid Vascular Tumors

Surg Pathol Clin. 2015 Sep;8(3):331-51. doi: 10.1016/j.path.2015.05.001.

Abstract

The diagnosis of vascular tumors is a challenging area in soft tissue pathology. Epithelioid vascular tumors pose a particular challenge. Due to the epithelioid morphology of the tumor cells, they can be misdiagnosed as a variety of other entities, including metastatic carcinoma or epithelioid sarcoma. Furthermore, it can be difficult to distinguish between different epithelioid vascular tumors. This review focuses on vascular tumors characterized by epithelioid endothelial cells, including epithelioid hemangioma, cutaneous epithelioid angiomatous nodule, epithelioid hemangioendothelioma, epithelioid sarcomalike hemangioendothelioma/pseudomyogenic hemangioendothelioma, and epithelioid angiosarcoma.

Keywords: Cutaneous epithelioid angiomatous nodule; Epithelioid angiosarcoma; Epithelioid hemangioendothelioma; Epithelioid hemangioma; Epithelioid sarcoma-like hemangioendothelioma; Intravascular epithelioid hemangioma; Pseudomyogenic hemangioendothelioma.

Publication types

  • Review

MeSH terms

  • Diagnosis, Differential
  • Hemangioendothelioma / diagnosis
  • Hemangioendothelioma / pathology
  • Hemangioendothelioma, Epithelioid / diagnosis
  • Hemangioendothelioma, Epithelioid / pathology
  • Hemangioma / diagnosis
  • Hemangioma / pathology
  • Hemangiosarcoma / diagnosis
  • Hemangiosarcoma / pathology
  • Humans
  • Vascular Neoplasms / diagnosis*
  • Vascular Neoplasms / pathology