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Acta Clin Belg. 1989;44(6):383-7.

Muscular fibrosis due to chronic intramuscular administration of narcotic analgesics.

Abstract

Chronic intramuscular injections, particularly of narcotic analgesics, are an uncommon cause of myopathy. We report two patients with pentazocine- and meperidine-related myopathy. Narcotic-induced muscular fibrosis and contractures must be considered in patients with a pattern of muscle involvement that does not conform to any recognized myopathy, but allows for self-administration of injections. Trauma due to needle puncture, repetitive infections and a local myotoxic effect of the drugs probably contribute to these lesions.

PMID:
2629447
[Indexed for MEDLINE]

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